Microelectrochemical Smart Needle for Real Time Minimally Invasive Oximetry.

ABSTRACT: A variety of brain disorders such as neural injury, brain dysfunction, vascular malformation, and neurodegenerative diseases are associated with abnormal levels of oxygen. Current methods to directly monitor tissue oxygenation in the brain are expensive and invasive, suffering from a lack of accuracy. Electrochemical detection has been used as an invasiveness and cost-effectiveness method, minimizing pain, discomfort, and injury to the patient. In this work, we developed a minimally invasive needle-sensor with a high surface area to monitor O₂ levels in the brain using acupuncture needles. The approach was to directly etch the iron from stainless steel acupuncture needles via a controlled pitting corrosion process, obtaining a high microporous surface area. In order to increase

SUBMITTER: Vieira D 

PROVIDER: S-EPMC7693384 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature