Linking Pharmacogenomic Information on Drug Safety and Efficacy with Ethnic Minority Populations.

ABSTRACT: Numerous prescription drugs' labeling contains pharmacogenomic (PGx) information to aid health providers and patients in the safe and effective use of drugs. However, clinical studies for such PGx biomarkers and related drug doses are generally not conducted in diverse ethnic populations. Thus, it is urgently important to incorporate PGx information with genetic characteristics of racial and ethnic minority populations and utilize it to promote minority health. In this project a bioinformatics approach was developed to enhance the collection of PGx information related to ethnic minorities to pave the way toward understanding the population-wide utility of PGx information. To address this challenge, we first gathered PGx information from drug labels. Second, we extracted data on the allele

SUBMITTER: Li D 

PROVIDER: S-EPMC7693750 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature