Genomic Features and Evolution of the Parapoxvirus during the Past Two Decades.
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ABSTRACT: Parapoxvirus (PPV) has been identified in some mammals and poses a great threat to both the livestock production and public health. However, the prevalence and evolution of this virus are still not fully understood. Here, we performed an in silico analysis to investigate the genomic features and evolution of PPVs. We noticed that although there were significant differences of GC contents between orf virus (ORFV) and other three species of PPVs, all PPVs showed almost identical nucleotide bias, that is GC richness. The structural analysis of PPV genomes showed the divergence of different PPV species, which may be due to the specific adaptation to their natural hosts. Additionally, we estimated the phylogenetic diversity of seven different genes of PPV. According to all available sequences,
SUBMITTER: Yao X
PROVIDER: S-EPMC7694016 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
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