Nanoparticle-Based Approaches towards the Treatment of Atherosclerosis.

ABSTRACT: Atherosclerosis, being an inflammation-associated disease, represents a considerable healthcare problem. Its origin remains poorly understood, and at the same time, it is associated with extensive morbidity and mortality worldwide due to myocardial infarctions and strokes. Unfortunately, drugs are unable to effectively prevent plaque formation. Systemic administration of pharmaceuticals for the inhibition of plaque destabilization bears the risk of adverse effects. At present, nanoscience and, in particular, nanomedicine has made significant progress in both imaging and treatment of atherosclerosis. In this review, we focus on recent advances in this area, discussing subjects such as nanocarriers-based drug targeting principles, approaches towards the treatment of atherosclerosis, utilizat

SUBMITTER: Prilepskii AY 

PROVIDER: S-EPMC7694323 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature