Speciation and adaptive evolution reshape antioxidant enzymatic system diversity across the phylum Nematoda.

ABSTRACT:

Background

Nematodes have evolved to survive in diverse ecological niches and can be a serious burden on agricultural economy, veterinary medicine, and public health. Antioxidant enzymes in parasitic nematodes play a critical role in defending against host oxidative stress. However, the features of the evolution of antioxidant enzymes in the phylum Nematoda remain elusive.

Results

Here, we systematically investigated the evolution and gene expression of antioxidant enzymes in the genomes of 59 nematodes and transcriptomes of 20 nematodes. Catalase has been independently lost in several orders, suggesting that it is unnecessary for some nematodes. Unlike in mammals, phospholipid hydroperoxide glutathione peroxidase is widely distributed in nematodes, among which it has evolve

SUBMITTER: Xu L 

PROVIDER: S-EPMC7694339 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature