Developmental stages in microbiota, bile acids, and clostridial species in healthy puppies.

ABSTRACT:

Background

The fecal microbiota, fecal bile acid concentrations, and abundance of Clostridium perfringens and Clostridium difficile are altered in acute and chronic gastrointestinal disease in adult dogs. However, less is known in young puppies.

Hypothesis/objectives

To determine composition of the fecal microbiota, assess development of fecal bile acid profiles, and determine the abundance of Clostridial species in puppies, young adult dogs, and adult dogs.

Animals

Healthy puppies from a whelping kennel (n = 53) and healthy client-owned dogs <1 year old (n = 20) were separated into 6 age groups, then compared to client-owned dogs over 1 year of age (n = 13).

Methods

Prospective observational study. Naturally voided fecal samples were analyzed by quantitative p

SUBMITTER: Blake AB 

PROVIDER: S-EPMC7694855 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature