Role of Daucus carota in Enhancing Antiulcer Profile of Pantoprazole in Experimental Animals.

ABSTRACT: The carrot plant (Daucus carota) and its components are traditionally reported for the management of gastric ulcers. This study was performed to evaluate the role of carrot when administered concurrently with a conventional antiulcer treatment, pantoprazole, in alleviating gastric and duodenal ulcers in female experimental animals. The study involved standard animal models to determine the ulcer preventive effect using pylorus ligation, ethanol, and stress induced acute gastric ulcer models and duodenal ulcer models involving cysteamine. Acetic acid-induced chronic gastric ulcer and indomethacin-induced gastric ulcer models were used to evaluate the ulcer healing effect. Carrot fruit (500 mg/kg) and its co-administration with pantoprazole produced significant protection in an ethanol- and

SUBMITTER: Asdaq SMB 

PROVIDER: S-EPMC7696376 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature