Study on the Influence of Chirality in the Threading of Calix[6]arene Hosts with Dialkylammonium Axles.

ABSTRACT: : The influence of chirality in calixarene threading has been studied by exploiting the "superweak anion approach". In particular, the formation of chiral pseudo[2]rotaxanes bearing a classical stereogenic center in their axle and/or wheel components has been considered. Two kind of pseudo[2]rotaxane stereoadducts, the "endo-chiral" and "exo-chiral" ones, having the stereogenic center of a cationic axle inside or outside, respectively, the calix-cavity of a chiral calixarene were preferentially formed with specifically designed chiral axles by a fine exploitation of the so-called "endo-alkyl rule" and a newly defined "endo-α-methyl-benzyl rule" (threading of ahexaalkoxycalix[6]arene with a directional (α-methyl-benzyl)benzylammoniumaxle occurs with an endo-α-methyl-benzyl preference). The

SUBMITTER: Talotta C 

PROVIDER: S-EPMC7696445 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature