Ultra-Processed Food Intake and Smoking Interact in Relation with Colorectal Adenomas.

ABSTRACT: Smoking and ultra-processed foods (UPFs), a substantial part of the western diet, have been suggested to have a potential carcinogenic effect, though epidemiologic data are lacking. We aimed to examine the association between high UPF intake and colorectal adenomas, and to test the interaction with smoking. In a case-control study among consecutive subjects undergoing colonoscopy in a tertiary center during 2010-2015, UPF intake and smoking were compared between cases with colorectal adenomas and controls. Within 652 participants (cases, n = 294 and controls, n = 358), high UPF intake (defined as percent of kcal from UPF above the study sample upper tertile) was positively associated with adenomas (Odds ratio (OR) = 1.75, 95% Confidence interval (CI) 1.14-2.68), advanced and proximal adeno

SUBMITTER: Fliss-Isakov N 

PROVIDER: S-EPMC7698317 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature