Blood Metabolomic Profiling Confirms and Identifies Biomarkers of Food Intake.

ABSTRACT: Metabolomics can be a tool to identify dietary biomarkers. However, reported food-metabolite associations have been inconsistent, and there is a need to explore further associations. Our aims were to confirm previously reported food-metabolite associations and to identify novel food-metabolite associations. We conducted a cross-sectional analysis of data from 849 participants (57% men) of the PopGen cohort. Dietary intake was obtained using FFQ and serum metabolites were profiled by an untargeted metabolomics approach. We conducted a systematic literature search to identify previously reported food-metabolite associations and analyzed these associations using linear regression. To identify potential novel food-metabolite associations, datasets were split into training and test datasets and

SUBMITTER: Langenau J 

PROVIDER: S-EPMC7698441 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature