Antibacterial Mode of Action of the <i>Daucus carota</i> Essential Oil Active Compounds against <i>Campylobacter jejuni</i> and Efflux-Mediated Drug Resistance in Gram-Negative Bacteria.

ABSTRACT: Today, an alarming rise of bacterial gastroenteritis in humans resulting from consuming Campylobacter-tainted foods is being observed. One of the solutions for mitigating this issue may be the antibacterial activity of essential oils. In the present research, we propose to study the antibacterial activity against Campylobacter and other Gram-negative bacteria of Daucus carota essential oil and its active molecules. In addition, a few chemically synthesized molecules such as (E)-methylisoeugenol, Elemicin, and eugenol were also studied. The results showed that the essential oil itself and its most active component, (E)-methylisoeugenol, exhibited bactericidal effects. Similar effects were detected using purified and chemically synthesized molecules. Also,

SUBMITTER: Dedieu L 

PROVIDER: S-EPMC7699865 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature