Long-Term Aspirin Use and 5-Year Survival in Healthy Adults: A Population-Based Cohort Study in South Korea.

ABSTRACT:

Purpose

We investigated whether long-term aspirin use is associated with 5-year all-cause mortality.

Materials and methods

Participants were individuals aged ≥40 years who were registered in the 2010 sample cohort database of the National Health Insurance Service in South Korea. Aspirin users were divided into three groups: continuous users (2006-2010), previous users (2006-2009), and new users (2010). Individuals with a history of coronary artery disease and cerebrovascular disease were excluded. Five-year all-cause mortality was defined as mortality due to any cause from January 1, 2011 to December 31, 2015. Data were analyzed by multivariable Cox regression.

Results

In total, 424444 individuals were included. Five-year all-cause mortality was 9% lower in continuous

SUBMITTER: Oh TK 

PROVIDER: S-EPMC7700872 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature