Comedonal and Cystic Fibrofolliculomas in Birt-Hogg-Dube Syndrome.

ABSTRACT:

Importance

The differential diagnosis of extensive open comedones includes inherited genetic syndromes and several acquired conditions. Birt-Hogg-Dube syndrome (BHD) is not typically included in the differential diagnosis of syndromes with comedonal lesions. Given the potentially life-threatening systemic complications associated with BHD, early recognition and diagnosis of the condition is important.

Observations

We describe comedonal or cystic fibrofolliculomas in 4 patients with BHD. Cutaneous lesions were identified on the face, neck, chest, and abdomen.

Conclusions and relevance

Comedonal or cystic fibrofolliculomas are a variant of fibrofolliculomas that have not previously been well characterized in patients with BHD and represent a novel diagnostic clue to its

SUBMITTER: Aivaz O 

PROVIDER: S-EPMC7701978 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature