Interbacterial competition and anti-predatory behaviour of environmental Vibrio cholerae strains.

ABSTRACT: Vibrio cholerae isolates responsible for cholera pandemics represent only a small portion of the diverse strains belonging to this species. Indeed, most V. cholerae are encountered in aquatic environments. To better understand the emergence of pandemic lineages, it is crucial to discern what differentiates pandemic strains from their environmental relatives. Here, we studied the interaction of environmental V. cholerae with eukaryotic predators or competing bacteria and tested the contributions of the haemolysin and the type VI secretion system (T6SS) to those interactions. Both of these molecular weapons are constitutively active in environmental isolates but subject to tight regulation in the pandemic clade. We showed that several environmental isolates resist amoebal grazing and that th

SUBMITTER: Drebes Dorr NC 

PROVIDER: S-EPMC7702109 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature