Risk factors and characterization of vitiligo and alopecia areata in patients with chronic graft-vs-host disease.

ABSTRACT:

Importance

Cutaneous manifestations of chronic graft-vs-host disease (GvHD) are highly variable and may recapitulate well-characterized autoimmune diseases, including systemic sclerosis and Sjögren syndrome. However, vitiligo and alopecia areata (AA) have not been well characterized in the chronic GvHD setting.

Objective

To determine laboratory markers, transplant-related factors, and other systemic manifestations associated with vitiligo and/or AA in patients with chronic GvHD.

Design, setting, and participants

A cross-sectional, retrospective study conducted by the National Institutes of Health (NIH) of 282 adult and pediatric patients with chronic GvHD seen under the NIH natural history protocol between 2004 and 2013.

Main outcomes and measures

Demographic,

SUBMITTER: Zuo RC 

PROVIDER: S-EPMC7703696 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature