The CroCo cross-link converter: a user-centred tool to convert results from cross-linking mass spectrometry experiments.

ABSTRACT:

Motivation

A variety of search engines exists for the identification of peptide spectrum matches after cross-linking mass spectrometry experiments. The resulting diversity in output formats complicates data validation and visualization as well as exchange with collaborators, particularly from other research areas.

Results

Here, we present CroCo, a user-friendly standalone executable to convert cross-linking results to a comprehensive spreadsheet format. Using this format, CroCo can be employed to generate input files for a selection of the commonly utilized validation and visualization tools.

Availability and implementation

The source-code is freely available under a GNU general public license at https://github.com/cschmidtlab/croco. The standalone executable is avail

SUBMITTER: Bender J 

PROVIDER: S-EPMC7703748 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature