PhyloMagnet: fast and accurate screening of short-read meta-omics data using gene-centric phylogenetics.

ABSTRACT:

Motivation

Metagenomic and metatranscriptomic sequencing have become increasingly popular tools for producing massive amounts of short-read data, often used for the reconstruction of draft genomes or the detection of (active) genes in microbial communities. Unfortunately, sequence assemblies of such datasets generally remain a computationally challenging task. Frequently, researchers are only interested in a specific group of organisms or genes; yet, the assembly of multiple datasets only to identify candidate sequences for a specific question is sometimes prohibitively slow, forcing researchers to select a subset of available datasets to address their question. Here, we present PhyloMagnet, a workflow to screen meta-omics datasets for taxa and genes of interest using gene-centric

SUBMITTER: Schon ME 

PROVIDER: S-EPMC7703773 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature