Genetic and reproductive consequences of consanguineous marriage in Bangladesh.

ABSTRACT:

Introduction

This study aimed to assess the prevalence, sociodemographic factors, reproductive consequences, and heritable disease burdens associated with consanguineous marriage (CM) in Bangladesh.

Methods

A total of 7,312 families, including 3,694 CM-families, were recruited from 102 locales of 58 districts of Bangladesh. Using a standard questionnaire, we collected medical history and background sociodemographic data of these families. Family history was assessed by pedigree analysis. Fertility, mortality, secondary sex ratio, selection intensity, lethal equivalents were measured using standard methods.

Results

The mean prevalence of CM in our studied population was 6.64%. Gross fertility was higher among CM families, as compared to the non-CM families (p < 0.05).

SUBMITTER: Anwar S 

PROVIDER: S-EPMC7703949 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature