Radiosensitivity-Related Genes and Clinical Characteristics of Nasopharyngeal Carcinoma.

ABSTRACT:

Materials and methods

Clinicopathological data of 185 patients with NPC treated at Nanfang Hospital of Southern Medical University between January 2013 and December 2014 were retrospectively analyzed. SPSS statistical software was used to analyze the clinicopathological data related to radiotherapy efficacy. Three patients who achieved complete remission and three with disease progression after CRT were selected. Differentially expressed genes (DEGs) were screened via mRNA microarray analysis of primary diagnostic endoscopy specimens.

Results

The peripheral blood leukocyte count, platelet count, and EBV-DNA copy number in NPC patients who were resistant to radiotherapy were higher than those in NPC patients who were sensitive to radiotherapy. The RobustRankAggreg (RRA) analy

SUBMITTER: Dai Y 

PROVIDER: S-EPMC7704138 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature