Vasomotor menopausal symptoms and risk of cardiovascular disease: a pooled analysis of six prospective studies.

ABSTRACT:

Background

Menopausal vasomotor symptoms (ie, hot flashes and night sweats) have been associated with unfavorable risk factors and surrogate markers of cardiovascular disease, but their association with clinical cardiovascular disease events is unclear.

Objective

To examine the associations between different components of vasomotor symptoms, timing of vasomotor symptoms, and risk of cardiovascular disease.

Study design

We harmonized and pooled individual-level data from 23,365 women in 6 prospective studies that contributed to the International Collaboration for a Life Course Approach to Women's Reproductive Health and Chronic Disease Events consortium. Women who experienced cardiovascular disease events before baseline were excluded. The associations between frequenc

SUBMITTER: Zhu D 

PROVIDER: S-EPMC7704910 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature