Uveal melanoma-associated cancers revisited.

ABSTRACT:

Background

Uveal melanoma (UM) is the most common primary ocular malignancy of adults. A small group of patients was found to express familial predisposition. Moreover, it may be preceded or followed by other malignancies elsewhere in the body. We aim to compare the incidence of UM and other associated cancers and study the factors that may influence each condition.

Patients and methods

We have collected the data from the Surveillance, Epidemiology and End Results database of nine US cancer registries for UM patients between 1973 and 2015. We calculated the standardised incidence ratios for single primary UM, first primary and second primary UM, and compared the groups for multiple factors.

Results

A total of 4946 patients were included in the study; 3863 with single

SUBMITTER: Alfaar AS 

PROVIDER: S-EPMC7705551 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature