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The modified arterial reservoir: An update with consideration of asymptotic pressure (P_∞) and zero-flow pressure (P_zf).

ABSTRACT: This article describes the modified arterial reservoir in detail. The modified arterial reservoir makes explicit the wave nature of both reservoir (P_res) and excess pressure (P_xs). The mathematical derivation and methods for estimating P_res in the absence of flow velocity data are described. There is also discussion of zero-flow pressure (P_zf), the pressure at which flow through the circulation ceases; its relationship to asymptotic pressure (P_∞) estimated by the reservoir model; and the physiological interpretation of P_zf . A systematic review and meta-analysis provides evidence that P_zf differs from mean circulatory filling pressure.

SUBMITTER: Hughes AD

PROVIDER: S-EPMC7705641 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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The modified arterial reservoir: An update with consideration of asymptotic pressure (P∞) and zero-flow pressure (Pzf).

Hughes Alun D AD Parker Kim H KH

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine 20200505 11

This article describes the modified arterial reservoir in detail. The modified arterial reservoir makes explicit the wave nature of both reservoir (Pres) and excess pressure (Pxs). The mathematical derivation and methods for estimating Pres in the absence of flow velocity data are described. There is also discussion of zero-flow pressure (Pzf), the pressure at which flow through the circulation ceases; its relationship to as ...[more]

PMID: 32367773

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Project description:During cold acclimation plants increase their freezing tolerance in response to low non-freezing temperatures. This is accompanied by many physiological, biochemical and molecular changes that have been extensively investigated. In addition, many cold acclimated plants become more freezing tolerant during exposure to mild, non-damaging sub-zero temperatures. There is hardly any information available about the molecular basis of this adaptation. However, Arabidopsis thaliana is among the species that acclimate to sub-zero temperatures. This makes it possible to use the molecular and genetic tools available in this species to identify components of sub-zero signal transduction and acclimation. Here, we have used microarrays and a qRT-PCR primer platform covering 1880 genes encoding transcription factors to monitor changes in gene expression in the accessions Columbia-0, Rschew and Tenela during the first three days of sub-zero acclimation at -3°C. The results indicate that gene expression during sub-zero acclimation follows a tighly controlled time-course. Especially AP2/EREBP and WRKY transcription factors may be important regulators of sub-zero acclimation, although the CBF signal transduction pathway seems to be less important during sub-zero than during cold acclimation. Globally, we estimate that approximately 5% of all Arabidopsis genes are regulated during sub-zero acclimation. Particularly photosynthesis-related genes were down-regulated and genes belonging to the functional classes of cell wall biosynthesis, hormone metabolism and RNA regulation of transcription were up-regulated. Collectively, these data provide the first global analysis of gene expression during sub-zero acclimation and allow the identification of candidate genes for forward and reverse genetic studies into the molecular mechanisms of sub-zero acclimation. We used whole genome microarrays to monitor changes in gene expression in the Arabidopsis thaliana accessions Columbia-0, Rschew and Tenela during three days of acclimation to sub-zero temperature at -3°C after cold acclimation

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The modified arterial reservoir: An update with consideration of asymptotic pressure (P_∞) and zero-flow pressure (P_zf).

Publications

The modified arterial reservoir: An update with consideration of asymptotic pressure (<i>P<sub>∞</sub></i>) and zero-flow pressure (<i>P<sub>zf</sub></i>).

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Dataset Information

The modified arterial reservoir: An update with consideration of asymptotic pressure (P∞) and zero-flow pressure (Pzf).

Publications

The modified arterial reservoir: An update with consideration of asymptotic pressure (&lt;i&gt;P&lt;sub&gt;∞&lt;/sub&gt;&lt;/i&gt;) and zero-flow pressure (&lt;i&gt;P&lt;sub&gt;zf&lt;/sub&gt;&lt;/i&gt;).

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets

The modified arterial reservoir: An update with consideration of asymptotic pressure (P_∞) and zero-flow pressure (P_zf).

The modified arterial reservoir: An update with consideration of asymptotic pressure (<i>P<sub>∞</sub></i>) and zero-flow pressure (<i>P<sub>zf</sub></i>).