Ontology highlight
ABSTRACT:
SUBMITTER: Liu W
PROVIDER: S-EPMC7705684 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Cell death discovery 20201130 1
Pseudogene pituitary tumor-transforming 3 (PTTG3P) is emerging as a key player in the development and progression of cancer. However, the biological role and clinical significance of PTTG3P in pancreatic ductal adenocarcinoma (PDAC) remain unclear. Here, we found that PTTG3P was significantly upregulated in PDAC tissues. Elevated PTTG3P expression correlated with larger tumor size and worse differentiation, and reduced overall survival. Bioinformatics and experimental evidence revealed that PTTG ...[more]