Characterization of an AA9 LPMO from Thielavia australiensis, TausLPMO9B, under industrially relevant lignocellulose saccharification conditions.

ABSTRACT:

Background

The discovery of lytic polysaccharide monooxygenases (LPMO) has changed our perspective on enzymatic degradation of plant biomass. Through an oxidative mechanism, these enzymes are able to cleave and depolymerize various polysaccharides, acting not only on crystalline substrates such as chitin and cellulose, but also on other polysaccharides, such as xyloglucan, glucomannan and starch. Despite their widespread use, uncertainties related to substrate specificity and stereospecificity, the nature of the co-substrate, in-process stability, and the nature of the optimal reductant challenge their exploitation in biomass processing applications.

Results

In this work, we studied the properties of a novel fungal LPMO from the thermophilic fungus Thielavia australiensis, T

SUBMITTER: Calderaro F 

PROVIDER: S-EPMC7706046 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature