Impact of Effective Global Tuberculosis Control on Health and Economic Outcomes in the United States.

ABSTRACT: Rationale: Most U.S. residents who develop tuberculosis (TB) were born abroad, and U.S. TB incidence is increasingly driven by infection risks in other countries.Objectives: To estimate the potential impact of effective global TB control on health and economic outcomes in the United States.Methods: We estimated outcomes using linked mathematical models of TB epidemiology in the United States and migrants' birth countries. A base-case scenario extrapolated country-specific TB incidence trends. We compared this with scenarios in which countries achieve 90% TB incidence reductions between 2015 and 2035, as targeted by the World Health Organization's End TB Strategy ("effective global TB control"). We also considered pessimistic scenarios of flat TB incidence trends in ind

SUBMITTER: Menzies NA 

PROVIDER: S-EPMC7706168 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature