Inhaled Corticosteroids Use and Risk of Invasive Pneumococcal Disease in a Population-based Study.

ABSTRACT: Rationale: The use of inhaled corticosteroids (ICS) is associated with increased pneumonia risk, but the risk of invasive pneumococcal disease (IPD) associated with ICS is not characterized.Objectives: The aim was to test the hypothesis that the use of ICS increases the risk of IPD.Methods: Cases were persons 20-65 years of age included in a Swedish national registry of invasive infection caused by Streptococcus pneumoniae classified as any IPD as well as the subset of IPD with pneumonia. The case index date was the day the infection was diagnosed. Six control subjects for each case (matched for sex, age, and region) were selected from the Swedish National Population Registry and were assigned the index date of their corresponding case. Current and past users of

SUBMITTER: Toren K 

PROVIDER: S-EPMC7706606 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature