A Functional Magnetic Resonance Imaging Approach for Language Laterality Assessment in Young Children.

ABSTRACT: Functional magnetic resonance imaging (fMRI) is a usable technique to determine hemispheric dominance of language function, but high-quality fMRI images are difficult to acquire in young children. Here we aimed to develop and validate an fMRI approach to reliably determine hemispheric language dominance in young children. We designed two new tasks (story, SR; Letter picture matching, LPM) that aimed to match the interests and the levels of cognitive development of young children. We studied 32 healthy children (6-10 years old, median age 8.7 years) and seven children with epilepsy (7-11 years old, median age 8.6 years) and compared the lateralization index of the new tasks with those of a well-validated task (verb generation, VG) and with clinical measures of hemispheric language dominance

SUBMITTER: Charbonnier L 

PROVIDER: S-EPMC7707083 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature