Retention of Value Representations Across Time in People With Schizophrenia and Healthy Control Subjects.

ABSTRACT:

Background

The current study aimed to further etiological understanding of the psychological mechanisms underlying negative symptoms in people with schizophrenia. Specifically, we tested whether negative symptom severity is associated with reduced retention of reward-related information over time and thus a degraded ability to utilize such information to guide future action selection.

Methods

Forty-four patients with a diagnosis of schizophrenia or schizoaffective disorder and 28 healthy control volunteers performed a probabilistic reinforcement-learning task involving stimulus pairs in which choices resulted in reward or in loss avoidance. Following training, participants indicated their valuation of learned stimuli in a test/transfer phase. The test/transfer phase was admi

SUBMITTER: Culbreth AJ 

PROVIDER: S-EPMC7708393 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature