Dimensional connectomics of anxious misery, a human connectome study related to human disease: Overview of protocol and data quality.

ABSTRACT: Disparate diagnostic categories from the Diagnostic and Statistical Manual of Mental Disorders (DSM), including generalized anxiety disorder, major depressive disorder and post-traumatic stress disorder, share common behavioral and phenomenological dysfunctions. While high levels of comorbidity and common features across these disorders suggest shared mechanisms, past research in psychopathology has largely proceeded based on the syndromal taxonomy established by the DSM rather than on a biologically-informed framework of neural, cognitive and behavioral dysfunctions. In line with the National Institute of Mental Health's Research Domain Criteria (RDoC) framework, we present a Human Connectome Study Related to Human Disease that is intentionally designed to generate and test novel, biologi

SUBMITTER: Seok D 

PROVIDER: S-EPMC7708855 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature