Obesity is associated with increased severity of disease in COVID-19 pneumonia: a systematic review and meta-analysis.

ABSTRACT:

Background

Obesity has been widely reported to be associated with the disease progression of coronavirus disease 2019 (COVID-19); however, some studies have reported different findings. We conducted a systematic review and meta-analysis to investigate the association between obesity and poor outcomes in patients with COVID-19 pneumonia.

Methods

A systematic review and meta-analysis of studies from the PubMed, Embase, and Web of Science databases from 1 November 2019 to 24 May 2020 was performed. Study quality was assessed, and data extraction was conducted. The meta-analysis was carried out using fixed-effects and random-effects models to calculate odds ratios (ORs) of several poor outcomes in obese and non-obese COVID-19 patients.

Results

Twenty-two studies (n = 12,5

SUBMITTER: Chu Y 

PROVIDER: S-EPMC7708895 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature