Cold adaptation does not alter ATP homeostasis during cold exposure in Drosophila melanogaster.

ABSTRACT: In insects and other ectotherms, cold temperatures cause a coma resulting from loss of neuromuscular function, during which ionic and metabolic homeostasis are progressively lost. Cold adaptation improves homeostasis during cold exposure, but the ultimate targets of selection are still an open question. Cold acclimation and adaptation remodels mitochondrial metabolism in insects, suggesting that aerobic energy production during cold exposure could be a target of selection. Here, we test the hypothesis that cold adaptation improves the ability to maintain rates of aerobic energy production during cold exposure by using ³¹ P NMR on live flies. Using lines of Drosophila melanogaster artificially selected for fast and slow recovery from a cold coma, we show that cold exposure does n

SUBMITTER: Williams CM 

PROVIDER: S-EPMC7708970 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature