Diagnosis of spinal lesions using perfusion parameters measured by DCE-MRI and metabolism parameters measured by PET/CT.

ABSTRACT:

Purpose

To investigate the correlation of parameters measured by dynamic-contrast-enhanced MRI (DCE-MRI) and ¹⁸F-FDG PET/CT in spinal tumors, and their role in differential diagnosis.

Methods

A total of 49 patients with pathologically confirmed spinal tumors, including 38 malignant, six benign and five borderline tumors, were analyzed. The MRI and PET/CT were done within 3 days, before biopsy. On MRI, the ROI was manually placed on area showing the strongest enhancement to measure pharmacokinetic parameters K^trans and k_ep. On PET, the maximum standardized uptake value SUV_max was measured. The parameters in different histological groups were compared. ROC was performed to differentiate between the two largest subtypes, metastases an

SUBMITTER: Zhang J 

PROVIDER: S-EPMC7709817 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature