Outcomes of isoniazid preventive therapy among people living with HIV in Kenya: A retrospective study of routine health care data.

ABSTRACT:

Introduction

Isoniazid preventive therapy (IPT) taken by People Living with HIV (PLHIV) protects against active tuberculosis (TB). Despite its recommendation, data is scarce on the uptake of IPT among PLHIV and factors associated with treatment outcomes. We aimed at determining the proportion of PLHIV initiated on IPT, assessed TB screening practices during and after IPT and IPT treatment outcomes.

Methods

A retrospective cohort study of a representative sample of PLHIV initiated on IPT between July 2015 and June 2018 in Kenya. For PLHIV initiated on IPT during the study period, we abstracted patient IPT uptake data from the National data warehouse. In contrast, we obtained information on socio-demographic, TB screening practices, IPT initiation, follow up, and outcomes from

SUBMITTER: Karanja M 

PROVIDER: S-EPMC7710039 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature