RNA sequencing data from osteochondroprogenitor populations in synovial joints of mice during murine model of rheumatoid arthritis.

ABSTRACT: The aim of this study was to analyze the transcriptome of TER119^-CD31^-CD45^-CD51⁺CD200⁺CD105^- population (further, CD200⁺), potential early osteocondroprogenitors, whose frequency is reduced in the joints of mice with antigen-induced arthritis (AIA) [1]. A population defined by similar surface markers has been previously identified as murine skeletal stem cells in bone [2]. In order to confirm their identity this population was compared to TER119^-CD31^-CD45^-CD51⁺CD200^-CD105⁺ (further, CD105⁺) cells, which possibly represent committed progenitors, or other non-progenitor population such as synovial fibroblasts. In order to asses changes in C

SUBMITTER: Lukac N 

PROVIDER: S-EPMC7711217 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature