Development and validation of a postoperative nomogram for predicting overall survival after endoscopic surgical management of olfactory neuroblastoma.

ABSTRACT:

Background

Olfactory neuroblastoma (ONB) is a rare malignancy arising in the nasal vault. Endoscopic resection has been reported to improve overall survival (OS). At present, clinicopathological predictors of the prognosis of ONB remain undefined.

Methods

Data including demographics, clinical characteristics and follow-up information of ONB patients treated with endoscopic surgery were collected. Risk factors on OS rates were investigated by LASSO and Cox analyses. A nomogram was developed and evaluated with internal validation. Risk groups were established according to patients' points in the nomogram.

Findings

154 ONB patients treated with surgery were included in this single center study. A nomogram based on multivariate Cox regression model including multiple tumo

SUBMITTER: Yang J 

PROVIDER: S-EPMC7711220 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature