A multicenter, prospective, observational study on montelukast monotherapy or montelukast-based combinations treating cough variant asthma.

ABSTRACT:

Background

Evidence of treatment against cough variant asthma (CVA) is insufficient for the clinical practice in China. We aimed at evaluating the real-world effectiveness of montelukast (MONT) alone or in combination with low-dose inhaled corticosteroids (ICS) and low-dose ICS plus long-acting beta-2-agonists (LABA) for Chinese CVA patients in a multicentre, prospective, cohort study.

Methods

Adult patients diagnosed with CVA defined as chronic cough >8 weeks with a positive bronchial provocation test and normal chest X-ray findings were enrolled at respiratory clinics. Study treatment followed routine clinical practice. The investigators initiated MONT by 10 mg/day alone or in combination with a low-dose ICS +/- LABA and followed up treatment outcomes for 4 weeks. The prim

SUBMITTER: Lin J 

PROVIDER: S-EPMC7711367 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature