A biomarker based severity progression indicator for COVID-19: the Kuwait prognosis indicator score.

ABSTRACT:

Background

COVID-19 is a worldwide pandemic that is mild in most patients but can result in a pneumonia like illness with progression to acute respiratory distress syndrome and death. Predicting the disease severity at time of diagnosis can be helpful in prioritizing hospital admission and resources.

Methods

We prospectively recruited 1096 consecutive patients of whom 643 met the inclusion criterion with COVID-19 from Jaber Hospital, a COVID-19 facility in Kuwait, between 24 February and 20 April 2020. The primary endpoint of interest was disease severity defined algorithmically. Predefined risk variables were collected at the time of PCR based diagnosis of the infection. Prognostic model development used 5-fold cross-validated regularized logit regression. The model was ext

SUBMITTER: Jamal MH 

PROVIDER: S-EPMC7711740 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature