High sensitivity Troponin-T for prediction of adverse events in patients with COVID-19.

ABSTRACT:

Background

High sensitivity cardiac troponin-T (hs-TnT) has been associated with mortality in patients hospitalized with COVID-19. We aimed to determine if hs-TnT levels and their timing are independent predictors of adverse events in these patients.

Design

Retrospective chart review was performed for all patients hospitalized at our institution between 23 March 2020 and 13 April 2020 who were found to be COVID-19-positive. Clinical, demographic, and laboratory variables including initial and peak hs-TnT were recorded. Univariable and multivariable analyses were completed for a primary composite endpoint of in-hospital death, intubation, need for critical care, or cardiac arrest.

Results

In the 276 patients analysed, initial hs-TnT above the median (≥17 ng/L) was asso

SUBMITTER: Singh N 

PROVIDER: S-EPMC7711742 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature