Anti-Tick Microbiota Vaccine Impacts Ixodes ricinus Performance during Feeding.

ABSTRACT: The tick microbiota is a highly complex ensemble of interacting microorganisms. Keystone taxa, with a central role in the microbial networks, support the stability and fitness of the microbial communities. The keystoneness of taxa in the tick microbiota can be inferred from microbial co-occurrence networks. Microbes with high centrality indexes are highly connected with other taxa of the microbiota and are expected to provide important resources to the microbial community and/or the tick. We reasoned that disturbance of vector microbiota by removal of ubiquitous and abundant keystone bacteria may disrupt the tick-microbiota homeostasis causing harm to the tick host. These observations and reasoning prompted us to test the hypothesis that antibodies targeting keystone bacteria may harm the

SUBMITTER: Mateos-Hernandez L 

PROVIDER: S-EPMC7711837 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature