Evolution of Developmental GATA Factors in Nematodes.

ABSTRACT: GATA transcription factors are found in animals, plants, and fungi. In animals, they have important developmental roles in controlling specification of cell identities and executing tissue-specific differentiation. The Phylum Nematoda is a diverse group of vermiform animals that inhabit ecological niches all over the world. Both free-living and parasitic species are known, including those that cause human infectious disease. To date, GATA factors in nematodes have been studied almost exclusively in the model system C. elegans and its close relatives. In this study, we use newly available sequences to identify GATA factors across the nematode phylum. We find that most species have fewer than six GATA factors, but some species have 10 or more. Comparisons of gene and protein structure sugges

SUBMITTER: Eurmsirilerd E 

PROVIDER: S-EPMC7712238 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature