Influenza Vaccination and Risk of SARS-CoV-2 Infection in a Cohort of Health Workers.

ABSTRACT: Vaccines may induce positive non-specific immune responses to other pathogens. This study aims to evaluate if influenza vaccination in the 2019-2020 season had any effect on the risk of SARS-CoV-2 confirmed infection in a cohort of health workers. During the first SARS-CoV-2 epidemic wave in Spain, between March and May 2020, a cohort of 11,201 health workers was highly tested by RT-qPCR and/or rapid antibody test when the infection was suspected. Later in June, 8665 of them were tested for total antibodies in serum. A total of 890 (7.9%) health workers were laboratory-confirmed for SARS-CoV-2 infection by any type of test, while no case of influenza was detected. The adjusted odds ratio between 2019-2020 influenza vaccination and SARS-CoV-2 confirmed infection was the same (1.07; 95% CI,

SUBMITTER: Martinez-Baz I 

PROVIDER: S-EPMC7712321 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature