Association between biomarkers and COVID-19 severity and mortality: a nationwide Danish cohort study.

ABSTRACT:

Objective

To evaluate the association between common biomarkers, death and intensive care unit (ICU) admission in patients with COVID-19.

Design

Retrospective cohort study. From electronic national registry data, we used Cox analysis and bootstrapping to evaluate associations between baseline levels of biomarkers and standardised absolute risks of death/ICU admission, adjusted for age and gender.

Setting

All hospitals in Denmark.

Participants

1310 patients aged ≥18 years admitted to hospital with COVID-19 from 27th of February to 1st of May 2020, with available biochemistry data.

Main outcome measures

A composite of death/ICU admission occurring within 30 days.

Results

Of the 1310 patients admitted to hospital (54.6% men; median age 73.6 years), 3

SUBMITTER: Hodges G 

PROVIDER: S-EPMC7712929 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature