Clinical characteristics of SARS-CoV-2 infection in children with cystic fibrosis: An international observational study.

ABSTRACT:

Background

The presence of co-morbidities, including underlying respiratory problems, has been identified as a risk factor for severe COVID-19 disease. Information on the clinical course of SARS-CoV-2 infection in children with cystic fibrosis (CF) is limited, yet vital to provide accurate advice for children with CF, their families, caregivers and clinical teams.

Methods

Cases of SARS-CoV-2 infection in children with CF aged less than 18 years were collated by the CF Registry Global Harmonization Group across 13 countries between 1 February and 7 August 2020.

Results

Data on 105 children were collated and analysed. Median age of cases was ten years (interquartile range 6-15), 54% were male and median percentage predicted forced expiratory volume in one second was 94%

SUBMITTER: Bain R 

PROVIDER: S-EPMC7713571 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature