Red blood cell product utilization in patients undergoing allogeneic stem cell transplantation.

ABSTRACT:

Background

The risk of transfusion reactions (TR) and the cost of blood has led to efforts to reduce blood use. We changed our practice to transfuse just one instead of two units of red blood cells (RBC) when hemoglobin ≤8 g/dL due to patient blood management (PBM) recommendations.

Methods and materials

We compared RBC utilization in patients receiving allogeneic HCT in the 10 months before (control arm) and 13 months after implementation of this new practice (intervention arm). We used regression models to estimate the independent effect of transfusion practice, length of hospitalization, the conditioning regimen, and donor type for patients who received at least one RBC unit. The outcome variable was total number of inpatient transfusions. In addition, a survey assessed th

SUBMITTER: Gastecki K 

PROVIDER: S-EPMC7713712 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature