Toward predictive modeling of catheter-based pulmonary valve replacement into native right ventricular outflow tracts.

ABSTRACT:

Background

Pulmonary insufficiency is a consequence of transannular patch repair in Tetralogy of Fallot (ToF) leading to late morbidity and mortality. Transcatheter native outflow tract pulmonary valve replacement has become a reality. However, predicting a secure, atraumatic implantation of a catheter-based device remains a significant challenge due to the complex and dynamic nature of the right ventricular outflow tract (RVOT). We sought to quantify the differences in compression and volume for actual implants, and those predicted by pre-implant modeling.

Methods

We used custom software to interactively place virtual transcatheter pulmonary valves (TPVs) into RVOT models created from pre-implant and post Harmony valve implant CT scans of 5 ovine surgical models of TOF to q

SUBMITTER: Jolley MA 

PROVIDER: S-EPMC7713792 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature