Feasibility and acceptability of early infant screening for sickle cell disease in Lagos, Nigeria-A pilot study.

ABSTRACT: In Nigeria, about 150000 babies are born annually with sickle cell disease (SCD), and this figure has been estimated to increase by 100% by the year 2050 without effective and sustainable control strategies. Despite the high prevalence, newborn screening for SCD which allows for early prophylactic treatment, education of parents/guardians and comprehensive management is not yet available. This study explored a strategy for screening in early infancy during the first and second immunization visits, determined the prevalence, feasibility and acceptability of early infant screening for SCD and the evaluation of the HemoTypeSC diagnostic test as compared to the high-performance liquid chromatography (HPLC) gold standard. A cross-sectional study was conducted in two selected primary health care

SUBMITTER: Oluwole EO 

PROVIDER: S-EPMC7714115 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature