The effect of ICSI in infertility couples with non-male factor: a systematic review and meta-analysis.

ABSTRACT:

Purpose

We performed a systematic review and meta-analysis of available literature to investigate the efficacy of the intracytoplasmic sperm injection (ICSI) in couples with non-male factor with respect to the clinical outcomes.

Methods

The literature search was based on EMBASE, PubMed, and the Cochrane Library. All studies published after 1992 until February 2020 and written in English addressing patients in the presence of normal semen parameters subjected to ICSI and in vitro fertilization (IVF) were eligible. Reference lists of retrieved articles were hand-searched for additional studies. The primary outcomes were fertilization rate, clinical pregnancy rate, and implantation rate; the secondary outcomes were good-quality embryo rate, miscarriage rate, and live birth rate

SUBMITTER: Geng T 

PROVIDER: S-EPMC7714870 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature