Investigating the Role of Diet and Exercise in Gut Microbe-Host Cometabolism.

ABSTRACT: We investigated the individual and combined effects of diet and physical exercise on metabolism and the gut microbiome to establish how these lifestyle factors influence host-microbiome cometabolism. Urinary and fecal samples were collected from athletes and less active controls. Individuals were further classified according to an objective dietary assessment score of adherence to healthy dietary habits according to WHO guidelines, calculated from their proton nuclear magnetic resonance (¹H-NMR) urinary profiles. Subsequent models were generated comparing extremes of dietary habits, exercise, and the combined effect of both. Differences in metabolic phenotypes and gut microbiome profiles between the two groups were assessed. Each of the models pertaining to diet healthiness, phy

SUBMITTER: Penney N 

PROVIDER: S-EPMC7716389 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature