Relationship between leukocyte counts and large vessel occlusion in acute ischemic stroke.

ABSTRACT:

Background

Neuroinflammation plays an important role in the pathogenesis of acute ischemic stroke (AIS) and peripheral leukocyte counts have proved to be independent predictors of stroke severity and outcomes. Clinical significance of large vessel occlusion (LVO) in AIS is increasing, as these patients are potential candidates for endovascular thrombectomy and likely to have worse outcomes if not treated urgently. The aim of our study was to assess the relationship between on admission leukocyte counts and the presence of LVO in the early phase of AIS.

Methods

We have conducted a cross-sectional, observational study based on a registry of consecutive AIS patients admitted up to 4.5 h after stroke onset. Blood samples were taken at admission and leukocyte counts were measured

SUBMITTER: Tarkanyi G 

PROVIDER: S-EPMC7716438 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature