A prospective study of pediatric and adolescent renal cell carcinoma: A report from the Children's Oncology Group AREN0321 study.

ABSTRACT:

Background

To the authors' knowledge, AREN0321 is the first prospective clinical study of pediatric and adolescent renal cell carcinoma (RCC). Goals of the study included establishing epidemiological, treatment, and outcome data and confirming that patients with completely resected pediatric RCC, including lymph node-positive disease (N1), have a favorable prognosis without adjuvant therapy.

Methods

From 2006 to 2012, patients aged <30 years with centrally reviewed pathology of RCC were enrolled prospectively.

Results

A total of 68 patients were enrolled (39 of whom were male; median age of 13 years [range, 0.17-22.1 years]). Stage was classified according to the American Joint Committee on Cancer TNM stage seventh edition as stage I in 26 patients, stage II in 7 pati

SUBMITTER: Geller JI 

PROVIDER: S-EPMC7717658 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature